Final product in my series of reviews from Regimen Lab – their C.R.E.A.M.! Be sure to check out my reviews on their Vitamin X and Wave Serum.
General Information on Regimen Lab C.R.E.A.M.
“C.R.E.A.M. is based on game-changing research that gives us a new understanding of how moisture moves through the skin. We use high-concentration ceramides to better replenish your skinβs natural barrier and aquaporins to help generate and lock in moisture.” – regimenlab.com
Price: $49 CAD/$39 USD
Amount: 50ml
Packaging: Opaque white bottle with an airless pump
pH: 4.5 – 5.0
Regimen Lab Vitamin C.R.E.A.M. Ingredients
Aqua, Glycerin, Isostearyl Isostearate, Isopropyl Isostearate, Isosorbide Dicaprylate, Bisabolol, Glyceryl Glucoside, Cetearyl Olivate, Sorbitan Olivate, Ceramide NP, Ceramide EOP, Ursolic Acid, Propanediol, Adipic Acid, Neopentyl Glycol Crosspolymer, Phospholipids, Cholesterol, Linolenic Acid, Linoleic Acid, Stearic Acid, Ammonium Acryloyldimethyltaurate/VP Copolymer, Tocopherol, Dimethoxymethyl Chromanol, Polyacrylamide, C13-14 Isoparaffin, Laureth 7, Citric Acid, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin, Chlorphenesin
For the skincare enthusiasts, I’m sure we have seen the “Why Most Ceramide Products are a Scam” reddit post. We felt shook if beloved moisturizer did not have the 3:1:1 (ceramides, cholesterol, essential fatty acids) ratio of ingredients.
What is this ratio and why are us skincare enthusiasts obsessed with it? The 1:1:1 or 3:1:1 molar ratio of ceramides, cholesterol and fatty acids is sought after in skincare. This is reportedly the ideal ratio seen to recover the skin barrier. Our skin is made up of these substances, it only makes sense that if we have an impaired skin barrier, we replenish it with what the skin lacks. The molar ratio has a range because the barrier recovery is dependent on factors such as skin type, use of topicals, etc. You can read more about it in the pdf down below. Note, it is a difficult read for us non-science lingo oriented folk:
Optimization of Physiological Lipid Mixtures for Barrier Repair
Regimen Lab states their C.R.E.A.M. has a 3:1:1:1 (note the extra 1) ratio:
- ceramides
- cholesterol
- essential fatty acids (EFAs)
- non-essential fatty acids (NEFAs)
Naturally, I was excited to try it out and see what impact it may have on my skin!
Quick Briefer:
- Ceramides – make up 50% of the outer layer of our skin – they help make up the glue that holds our skin cells together, keeping our skin hydrated.
- Cholesterol – make up 25% of the lipids on the outer layer of our skin
- Fatty Acids – make up 15% of the lipids on the outer layer of our skin
From my understanding (a non-science profession one), the ratio C.R.E.A.M. is as follows:
(This is based on their 5% of the following ingredients and how it’s ordered in the INCI list)
2.5% Ceramides (NP + EOP) : 0.833% Cholesterol + Phospholipids : 0.833% Lineonic Acid (Omega 3, essential) + Linoleic Acid (Omega 6) : 0.833% Stearic Acid
Now that we (including I) understand this 3:1:1:1 ratio offered in C.R.E.A.M., time for the rest of the standout ingredients!
- 5% Glycerin – also an ingredient naturally occurring in our skin that acts as a humectant.
- 2% Isosorbide Dicaprylate and 2% Glyceryl Glucoside – according to Regimen Lab, help activate more efficient hydration alongside Glycerin.
- 2% Bisabolol – soothing.
- 2% Ursolic Acid Liposomes – according to Regimen Lab, this ingredient helps support the skin barrier.
Tocopherol – antioxidant.
I’m glad you made it through this skinthusiast perspective about the madness behind this 3:1:1 ratio! Now on to my personal use of C.R.E.A.M.
My Experience Using Regimen Lab C.R.E.A.M.



As you may have guessed, I used Regimen Lab C.R.E.A.M. as my moisturizer lol. In the morning, I used it after all the serums, before SPF (of course). At night, it was the last step in my skincare routine. I applied 2 pumps of C.R.E.A.M. for my face and neck in the summer. I find myself doubling the amount now that we are in the cold season!
The finish feels nice and velvety and it just gives the skin a nice healthy look. Unfortunately in the summer and now fall months, it did not moisturize enough. The moisture would disappear, especially if I was inside majority of the day. My skin felt dry to the touch and my face would start to feel a tad tight. My face would feel comfortable if I was out and about, producing tidbits of my own oils mixed into C.R.E.A.M. Overnight I found myself waking up with dry, slightly tight skin if I used it on its own. This plus the weather change is what prompted me to increase the amount I used. While the feeling did improve a bit, I still sometimes find myself applying my go-to moisturizer as a safeguard.
I tried using C.R.E.A.M. in combination with the Wave Serum. Basically, I wasn’t a fan of this mixture; I’d rather use the two separately. I also used it as a “supplemental” moisturizing product in my routine. I just wasn’t into the feel and finish of it on my skin. I preferred the Wave Serum for this purpose.
My Final Thoughts on Regimen Lab C.R.E.A.M.
I appreciate the formulation of Regimen Lab’s C.R.E.A.M. in that it’s offering us skincare nerds that “golden” ratio of barrier repairing ingredients. Unfortunately it doesn’t really suit my routine at the moment. It is not rich enough for my dry skin to use as a moisturizer, I just use too much for 50ml. I wasn’t a fan of mixing it with the Wave Serum, and on its own I didn’t really notice any significant impact it had on my skin’s health. I don’t think I am the right candidate for this skincare product. it may be better suited to those who are in dire need of something repairing.
Where to Buy: Regimen Lab Official Website
As always, I hope you find content like this helpful and informative!
xo, M